Integrin VLA-5 Negative Primary Plasma Cell Leukemia.
نویسندگان
چکیده
منابع مشابه
Leptomeningeal metastases from primary plasma cell leukemia.
H ere, we describe a 52-year-old woman with a history of primary plasma cell leukemia (PCL) who achieved complete remission after the tandem of autologous and nonmyeloablative allogeneic stem cell transplantation (SCT). Nine months after the allogeneic SCT, she presented with oculomotor and trochlear nerve palsy (diplopia, ptosis of the right upper eye lid, and dilated right pupil). Physical ex...
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Acute lymphoblastic leukemia bearing the Philadelphia chromosome is among the most difficult types of ALL to cure. However, the advent of targeted tyrosine kinase inhibitor (TKI) imatinib has ushered in a new era of treatments that have the potential to be less toxic to patients. Integrins and tyrosine kinases play important roles in mediating and transducing signals for cell survival and suppr...
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A 76-year-old female was diagnosed as having primary plasma cell leukemia (PCL), based on abundant atypical plasma cells in the circulation and bone marrow, monoclonal kappa light chain in the serum and urine, the immunophenotype of the plasma cells and the lack of preceding multiple myeloma. The patient was treated with melphalan and prednisolone (MP), and complete remission (CR) was achieved;...
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High-output cardiac failure in multiple myeloma (MM) is related to arteriovenous shunting in bone infiltrate disease. We describe such a complication in a patient with primary plasma cell leukemia (pPCL) without bone disease. We review the mechanisms that could be involved. As previously described, traditional cardiac failure therapy is not effective. pPCL therapy should not be delayed.
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 1993
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.32.565